Chambers was born in Springfield, Ohio, to Pam and John Chambers of Irish and German descent. He has a twin brother named Jason, one older brother Chip (John); and two older sisters, Mia and Susan. He and his twin brother visited hospitals often as children due to frequent bouts with pneumonia. He attended Springfield Christian elementary school. He has five children with his wife, Keisha: Isabella Read more...

Chambers was discovered by a modeling scout on the Paris Metro and went on to represent Calvin Klein in a fragrance campaign. He worked throughout Europe, Japan, and the United States for CK, Armani, and Dolce & Gabbana1. After deciding on an acting career, he moved to New York, where he studied at H.B. Studios for four years. That landed him a few television roles, including Another World and Read more...

Justin W. Chambers (born July 11, 1970) is an American actor and former Calvin Klein male fashion model. As of 2005, he is starring in the ABC drama series Grey's Anatomy as Dr. Alex Karev.