Biggs began acting at the age of five. In 1992, he made his television debut in the short lived Fox network series Drexell's Class. He also made a one-off HBO special, The Fotis Sevastakis Story, but due to licencing arguments, it was never aired. That same year, Biggs debuted on Broadway in Conversations with My Father, which helped pave the way for Biggs to participate in the daytime soap opera, As the World Turns. He was nominated for the award of Best Younger Actor at the daytime Emmy awards for his role in that soap.

Biggs attended New York University briefly from 1996-1997, but soon afterwards, he returned to pursue his acting. And so he would be seen again in another short lived television series, 1997's Camp Stories. He went on to make American Pie, which went on to become an international hit that has spawned two sequels. After that, Biggs accepted starring roles in movies such as Loser in 2000, and others. In 2004-2005 season Biggs portrayed an Orthodox Jew in Danie