"Midlife Crisis" has been used in Grand Theft Auto: San Andreas and Tony Hawk's Underground 2, and "From out of Nowhere" was featured in EA Sports' Madden NFL 2005 and NHL 2005. "Epic" is featured in the new "Street Fighter IV" trailer. "Epic" and "We Care a Lot" are playable tracks in Rock Band, the latter being a downloadable track.

"Easy" was subsequently used in a commercial for Levi's in 2006. A portion of the chorus from "We Care a Lot" has been used as the theme song for the Discovery Channel's Dirty Jobs. The lyrics to "Epic" were also featured in the Manga graphic novel The Dirty Pair: A Plague of Angels, as characters recite lines from the song. "Falling to Pieces" was featured in Ridley Scott's 2001 war movie Black Hawk Down, as background music while soldiers prepare for their mission. According to the Mark Bowden book upon which the film is based, when the soldiers were preparing for the actual 1993 mission, Guns N' Roses' "Welcome to the Jungle" was playing on t