Pompeo was born in Everett, Massachusetts, the daughter of Joseph, a salesman, and Kathleen Pompeo. Pompeo is of Irish and Italian descent and was raised Catholic. Her grandfather was born in Gesualdo, a village in Province of Avellino, Italy.[citation needed] Her mother passed away when she was four years old and her father remarried soon after her mother's death. She was nicknamed the pencil and Read more...

Determined to succeed in acting, Pompeo moved to Los Angeles in 2001. A turning point came when she was selected by director Brad Silberling in 2002 for a role in his film Moonlight Mile playing Jake Gyllenhaal's sympathetic love interest. She also appeared in the film Daredevil playing Matt Murdock's (Ben Affleck) secretary Karen Page, but most of her scenes were deleted from the theatrical version Read more...

Pompeo married record producer Chris Ivery on November 9, 2007 at New York's City Hall, with Mayor Michael Bloomberg serving as their witness. They met in 2003 when mutual friends introduced them at a Whole Foods Market, and began dating six months later. They later discovered that they grew up in Boston 10 miles from each other. They now reside in Los Angeles.