Feldman did print campaigns for Rampage, Jaguar, Fila, Wella, Zanetti for Italy, Diesel and Tornado in Israel, Panasonic in Japan, and Platini Jeans in North and South America. She also starred in television commercials for Panasonic Viera, Halifax in Great Britain, and a recent Movietickets.com spot, as well as a few music videos, such as Justin Timberlake's "Senorita" and Sugar Ray's "It's So Easy". Donna was featured in Maxim Magazine's annual Hot 100 List of 2005 as #84, and she was the awards hostess for the 2005 Academy Awards.

In 2005, Feldman became a model on the first season of NBC's new game show, Deal or No Deal. She held case 22 for most of the season. After the first season, Donna made the choice to leave Deal or No Deal when she became a cast member of My Network TV's primetime soap Fashion House, playing temptress Gloria which began airing on Sept 5, 2006. Fashion House is currently airing in over 50 Countries. She was featured in a layout in the Feb. 2007 issu