Krumholtz was born in Queens, New York, the son of Judy, a dental assistant, and Michael Krumholtz, a postal worker. He grew up in a "very working-class, almost poor" Jewish family. His mother moved from Hungary to the U.S. in 1956.

Krumholtz began his acting career at the age of thirteen when he followed his friends to an open audition for the Broadway play Conversations with My Father (1992). Though he did not expect to get the part, and did not even care, he won the role of Young Charlie opposite Judd Hirsch, Tony Shalhoub, and Jason Biggs (also making his Broadway debut). Soon after his run on Broadway, Krumholtz co-starred Read more...

Krumholtz is good friends with Judd Apatow and his Freaks and Geeks co-stars. He appears in two documentaries on the Knocked Up DVD (one being staged and the other being genuine). "Gummy: The Sixth Roommate" tells the true story of how David dropped out of the film to play the lead part in a Woody Allen movie in Paris that got canceled before production, and Apatow would not write him back into Read more...