Her first role was as a guest in the Showtime sci-fi series Jeremiah, and she has guest starred in numerous television series since, including a recurring part in The L Word.

Her first permanent series role was in the short-lived ABC series Veritas: The Quest; her second would be the series for which she is most well-known, the CBS sitcom How I Met Your Mother, where she plays television reporter Robin Scherbatsky, also a Canadian.

Joss Whedon has joked that she was his choice for the lead role in the film adaption of Wonder Woman after he left the project.